Stiff Person Syndrome

Web Stiff person syndrome SPS is a rare progressive syndrome that affects the nervous system specifically the brain and spinal cord. It causes progressive muscle stiffness and painful spasms that can be triggered by a variety of things including sudden movement cold temperature or unexpected loud noises.

Stiff Person Syndrome With Evidence Of Nonspecific Focal Myositis Secondary To Sustained Muscle Contraction A Case Report Sciencedirect

Spasms can generate enough force to fracture bone.

. The stiffness primarily affects the truncal muscles and is superimposed by spasms resulting in postural deformities. Web Stiff Person Syndrome SPS is an autoimmune and neurological disorder that can make the muscles in the torso and limbs alternate between rigidity and spasms. Web Stiff person syndrome SPS is a very rare disease affecting only one or two people per million.

The cause of this extremely rare disease is still unknown. SPS is strongly correlated with autoimmune diseases and it is usual to find high titers of antibodies against acid decarboxylase. Symptoms may include extreme muscle stiffness rigidity and painful spasms in the trunk and limbs severely impairing mobility.

SPS is characterized by fluctuating muscle rigidity in the trunk and limbs and a heightened sensitivity to stimuli such as noise touch and emotional distress which can set off muscle spasms. Web Stiff-person syndrome SPS is a rare neurological disorder with features of an autoimmune disease. Muscle rigidity sporadic muscle spasms and chronic muscle pain characterize SPS.

Web Stiff person syndrome is more likely seen in people with certain types of diseases including. Web Stiff-person syndrome SPS also known as stiff-man syndrome SMS 1 is a rare neurologic disorder of unclear cause characterized by progressive rigidity and stiffness. Certain cancers including breast lung kidney thyroid colon and Hodgkins lymphoma.

Web Stiff-person syndrome SPS is a rare and disabling central nervous system disorder with no satisfactory treatment. Autoimmune disorders including diabetes thyroiditis vitiligo and pernicious anemia.

The Stiff Person Syndrome Research Foundation

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Stiff Person Syndrome

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